Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia. This review summarises the classification and clinical and therapeutic aspects of cryoglobulinaemic vasculitis and glomerulonephritis.
- ANCA, antineutrophil cytoplasmic antibody
- HBV, hepatitis B virus
- HCV, hepatitis C virus
- MPGN, membranoproliferative glomerulonephritis
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Competing interests: None.