Postgrad Med J 82:259-266 doi:10.1136/pgmj.2005.039768
  • Review

Aetiology, diagnosis, and management of hypopituitarism in adult life

  1. V K B Prabhakar1,
  2. S M Shalet2
  1. 1Department of Diabetes and Endocrinology, Stepping Hill Hospital, Stockport, Cheshire, UK
  2. 2Christie Hospital, Manchester, UK
  1. Correspondence to:
 Dr V K B Prabhakar
 Department of Diabetes and Endocrinology, Lime House, Stepping Hill Hospital, Stockport, Cheshire SK2 7JE, UK; kaari_24{at}
  • Received 21 July 2005
  • Accepted 19 September 2005


Hypopituitarism is a complex medical condition associated with increased morbidity and mortality, requires complicated treatment regimens, and necessitates lifelong follow up by the endocrinologist. The causes, clinical features, and the management of hypopituitarism including endocrine replacement therapy are considered in this review article.


  • Funding: none.

  • Competing interests: none declared.