Article Text

PDF
Gall stones and chronic pancreatitis: the black box in between
  1. M-X Yan1,2,
  2. Y-Q Li1
  1. 1Department of Gastroenterology, Shandong University Qilu Hospital, Shandong Province, China
  2. 2Department of Gastroenterology, Shandong University School of Clinical Medicine, Shandong Qianfoshan Hospital, Shandong Province, China
  1. Correspondence to:
 Dr M-X Yan
 Department of Gastroenterology, Shandong University School of Clinical Medicine, Shandong Qianfoshan Hospital, 250014, 66 Jingshi Road, Jinan, Shandong Province, China; milsonyan{at}163.com

Abstract

The relation between gall stones and chronic pancreatitis is uncertain; there are differing opinions on this issue. Firstly, gall stones are the most common reason for acute pancreatitis, but it cannot cause chronic pancreatitis. Secondly, a connection between gall stones and chronic inflammation of the pancreas might exist. Numerous studies or investigations have shown that changes associated with chronic pancreatitis are common in gallstone patients. Although it seems that gall stones might be a cause of chronic pancreatitis according to these findings, clinical and experimental studies are still needed for confirmation, and further studies are required to determine the mechanisms involved.

  • SO, sphincter of Oddi
  • CBD, common bile duct
  • CCK, cholecystokinin
  • GACP, gallstone associated chronic pancreatitis
  • ERCP, endoscopic retrograde cholangiopancreatography
  • gall stone
  • cholelithiasis
  • chronic pancreatitis
  • pathogenesis

Statistics from Altmetric.com

Footnotes

  • Funding: none.

  • Conflicts of interest: none.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.