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Postgrad Med J 2006;82:e3 doi:10.1136/pgmj.2005.036483
  • Electronic pages

Acquired haemophilia heralded by bleeding into the oral mucosa in a patient with bullous pemphigoid, rheumatoid arthritis, and vitiligo

  1. R S Patel1,
  2. K E Harman2,
  3. C Nichols1,
  4. R M Burd2,
  5. S Pavord1
  1. 1Department of Haemostasis and Thrombosis, Directorate of Haematology, Leicester Royal Infirmary, Leicester, UK
  2. 2Department of Dermatology, Leicester Royal Infirmary
  1. Correspondence to:
 Dr R S Patel
 Department of Haemostasis and Thrombosis, Directorate of Haematology, Leicester Royal Infirmary, Leicester LE1 5WW, UK; rakeshspatel{at}hotmail.com
  • Received 26 April 2005
  • Accepted 4 July 2005

Abstract

Acquired haemophilia is rare and potentially fatal, with a mortality of 20% if left untreated. There is a strong association with other autoimmune diseases. This report describes a patient with rheumatoid arthritis, vitiligo, and bullous pemphigoid where the diagnosis of acquired haemophilia was made after an extensive bleed into a bullous lesion in the buccal mucosa. This case highlights some of the potential complications of acquired haemophilia and its treatment.

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