Amiodarone toxicity presenting as pulmonary mass and peripheral neuropathy: the continuing diagnostic challenge
- 1Department of Internal Medicine A, Bnai-Zion Medical Centre and “Rappaport Family” Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
- 2Department of Internal Medicine C, Bnai-Zion Medical Center and “Rappaport Family” Faculty of Medicine, Technion-Israel Institute of Technology
- Correspondence to: Dr J E Naschitz Department of Internal Medicine A, Bnai-Zion Medical Centre, Haifa 31048, PO Box 4940, Israel;
- Received 19 August 2005
- Accepted 16 October 2005
A 64 year old man receiving long term amiodarone treatment presented with dyspnea, cough, and weight loss. Radiographs and computed tomography showed a lung mass with associated multiple pulmonary nodules. Biopsies of the pulmonary mass showed foamy histiocytes without malignant cells. However, findings on FDG-PET scan were consistent with a malignant tumour. These findings on computed tomography and PET scan and the unusually late resolution of the pulmonary lesions after withdrawal of amiodarone treatment posed a challenging diagnostic problem.
Conflicts of interest: none declared.