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Postgrad Med J 2005;81:e12 doi:10.1136/pgmj.2004.029611
  • Electronic pages

Gastrointestinal involvement in POEMS syndrome: a novel clinical manifestation

  1. S Dogan1,
  2. Y Beyazit1,
  3. A Shorbagi1,
  4. S Köklü2,
  5. S Ustunel3,
  6. N Guler4,
  7. A Uner5
  1. 1Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey
  2. 2Department of Gastroenterology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey
  3. 3Hacettepe University, Faculty of Medicine
  4. 4Department of Medical Oncology, Hacettepe University, Faculty of Medicine
  5. 5Department of Pathology, Hacettepe University, Faculty of Medicine
  1. Correspondence to:
 Dr S Köklü
 Tıp Fakültesi caddesi, 259/3, Mamak, Ankara, Turkey; gskokluyahoo.com
  • Received 11 October 2004
  • Accepted 9 March 2005

Abstract

POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) is characterised by a rare multisystem disorder of unknown pathogenesis. Although its pathophysiology is not well understood, overexpression of proinflammatory cytokines has been implicated. Gastrointestinal system disorders have not been reported among the components of the syndrome. A case is reported of POEMS syndrome with gastrointestinal involvement shown by gastrointestinal endoscopy.

Footnotes

  • Funding: none.

  • Competing interest: none.

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