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Postgrad Med J 2005;81:266-267 doi:10.1136/pgmj.2004.026369
  • Adverse drug reaction

Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient

  1. J L Cheong,
  2. R Bucknall
  1. Rheumatic Diseases Unit, Royal Liverpool University Hospital NHS Trust, Liverpool, UK
  1. Correspondence to:
 Dr J L Cheong
 Rheumatic Diseases Unit, Link 7Z, Royal Liverpool University Hospital NHS Trust, Prescot Road, Liverpool L7 8XP, UK; jelai_cheonghotmail.com
  • Received 1 July 2004
  • Accepted 7 August 2004

Abstract

A 55 year old woman, known to have systemic lupus erythematosus and protein S deficiency, presented with sudden onset of visual loss in the left eye. Three days previously, she took a herbal phytoestrogen preparation for relief of her menopausal symptoms. Ophthalmological assessment showed a left inferior hemiretinal vein thrombosis. The temporal relation between the onset of visual symptoms and ingestion of this herbal preparation suggested that in this patient with a prior non-manifest prothrombotic tendency, there may be an association between the development of retinal vein thrombosis and herbal phytoestrogen use.

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