Article Text

PDF

Pathological fracture in a pregnant woman
  1. P Chaturvedi,
  2. A Puri,
  3. M G Agarwal,
  4. P S Pai,
  5. K A Pathak,
  6. D A Chaukar,
  7. M S Deshpande,
  8. A K Decruz
  1. Department of Surgery, Tata Memorial Hospital, Mumbai, India
  1. Correspondence to:
 Dr Pankaj Chaturvedi
 Assistant Professor, Tata Memorial Hospital, EB Road, Parel, Mumbai 400 012; pankajch37yahoo.com

Statistics from Altmetric.com

Answers on p 743.

A 27 year old woman presented in the third trimester of pregnancy with a history of gradually progressive pain in the upper end of her humerus. There was no significant medical history or any other associated illness. Magnetic resonance imaging (MRI) revealed a pathological fracture with extensive marrow replacement of the upper humerus and an associated large soft tissue mass in the upper arm (fig 1). A core needle biopsy documented benign giant cells. The patient was treated with excision and replacement with a prosthesis.

Figure 1

 MRI showing a lytic lesion with pathological fracture and soft tissue extension in the upper end of the humerus.

QUESTIONS

  1. What is the differential diagnosis based on the history and the MRI (giant cell tumour, brown tumour, chondrosarcoma, secondaries in the bone)?

  2. What other relevant blood investigation should be ordered in such patients (calcium, parathyroid hormone, alkaline phosphatase, acid phosphatase)?

View Abstract

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Self assessment answers
    The Fellowship of Postgraduate Medicine
  • Self assessment answers
    The Fellowship of Postgraduate Medicine