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Postgrad Med J 2004;80:363-365 doi:10.1136/pgmj.2003.015297
  • Case report

Dramatic levodopa responsiveness of dystonia in a sporadic case of spinocerebellar ataxia type 3

  1. R Nandagopal,
  2. S G K Moorthy
  1. Department of Neurology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
  1. Correspondence to:
 Dr R Nandagopal
 Department of Neurology, Sri Venkateswara Institute of Medical Sciences, Tirupati-517 507, Andhra Pradesh, India; rnandagopalyahoo.com
  • Received 23 September 2003
  • Accepted 8 November 2003

Abstract

A genetically confirmed case of spinocerebellar ataxia type 3 (SCA 3), presenting with disabling foot dystonia, peripheral neuropathy, and minimal cerebellar signs is reported. The dystonia improved dramatically with levodopa treatment in the absence of additional parkinsonian feature. A trial of levodopa for dystonia in SCA 3 may be of therapeutic benefit, at least in the initial stage of the disease.

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