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Postgrad Med J 2004;80:320-327 doi:10.1136/pgmj.2003.013508
  • Review

Evolving immunotherapeutic strategies in bladder and renal cancer

  1. T R L Griffiths,
  2. J K Mellon
  1. Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester General Hospital, Leicester, UK
  1. Correspondence to:
 Mr T R L Griffiths
 Department of Cancer Studies and Molecular Medicine, University of Leicester, Clinical Sciences Unit, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK; TRLG1le.ac.uk
  • Received 7 August 2003
  • Accepted 3 November 2003

Abstract

For patients with urological cancers, immunotherapy is currently a treatment option for metastatic renal cell carcinoma, and those with “high risk” superficial bladder cancers. In this review, our current understanding of tumour immune escape is discussed. The principles and role of current immunotherapies for these tumours are described, and new areas of immunotherapeutic promise are highlighted.

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