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Postgrad Med J 79:715
  • LETTER

Update on irritable bowel syndrome

Table 1

Published literature on the efficacy, safety, and tolerability of tegaserod

Tegaserod, a 5-HT4 receptor partial agonist, relieves symptoms of IBS in patients with abdominal pain, bloating, and constipation Aliment Pharmacol Ther2001;:–66
Safety and tolerability of tegaserod in patients with IBS and symptoms of diarrhoea Am J Gastroenterol2002;:–81
Long term safety of tegaserod in patients with constipation-predominant IBS Aliment Pharmacol Ther2002;:–8
A randomised, double blind, placebo controlled trial of tegaserod in female patients suffering from IBS with constipation Aliment Pharmacol Ther2002;:–88
Tegaserod, a 5-hydroxytryptamine type 4 receptor partial agonist, is devoid of electrocardiographic effects Am J Gastroenterol2002;:–27
An Asian-Pacific, double blind, placebo controlled, randomised study to evaluate the efficacy, safety, and tolerability of tegaserod in patients with IBS Gut2003;:–6

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