Postgrad Med J 79:295-296 doi:10.1136/pmj.79.931.295
  • Adverse drug reactions

Recurrent aseptic meningitis due to different non-steroidal anti-inflammatory drugs including rofecoxib

  1. M L Ashwath,
  2. H P Katner
  1. Department of Internal Medicine, Mercer University School of Medicine, Macon, Georgia
  1. Correspondence to:
 Dr Ashwath;
  • Received 20 December 2002
  • Accepted 11 February 2003


Aseptic meningitis can be caused by viruses, drugs, and connective tissue disorders. The most common drugs causing it include antibiotics like trimethoprim-sulfamethoxazole, non-steroidal anti-inflammatory drugs (NSAIDs), intravenous immunoglobulins, intrathecal agents, vaccines, and monoclonal antibodies. A patient who had aseptic meningitis from three different NSAIDs including rofecoxib is presented.