Modern treatment of acromegaly
- Correspondence to: Dr Zayd Merza, Endocrine and Diabetes Centre, Northern General Hospital, Sheffield S5 7AU, UK;
- Received 27 November 2002
- Accepted 21 December 2002
Acromegaly is an endocrine disorder characterised by increased morbidity and mortality. It is usually caused by a growth hormone secreting pituitary adenoma and is manifested by a variety of clinical features. Surgery is usually the treatment of choice, however over the last few years, several new methods of treatment have been developed. A recent consensus on the targets for treatment has led to multiple studies being conducted to assess the efficacy of the currently available options. This review examines the evidence for and against these treatments.
- GHRH, growth hormone-releasing hormone
- GKS, gamma knife radiosurgery
- IGF-1, insulin-like growth factor-1