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Postgrad Med J 2002;78:623-624 doi:10.1136/pmj.78.924.623
  • Case report

Possible functional regression of insulinoma with prolonged octreotide

  1. C E H Craig,
  2. I W Gallen
  1. Diabetes Centre, Wycombe General Hospital, High Wycombe, Buckinghamshire HP11 2TT, UK
  1. Correspondence to:
 Dr Gallen;
 iangallen{at}aol.com
  • Received 21 January 2002
  • Accepted 19 June 2002

Abstract

A 75 year old woman was treated for over three years with the somatostatin analogue, octreotide for an insulinoma. She had presented in a hypoglycaemic coma. C-peptide and insulin concentrations were both raised and an area of increased vascularity within the pancreas was shown by angiography. No lesion was found at laparotomy and no resection was performed. After over three years of octreotide treatment it was withdrawn for a week. Her insulin and C-peptide concentrations were greatly reduced at this time and remained so.

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