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Postgrad Med J 2002;78:51-52 doi:10.1136/pmj.78.915.51
  • Case report

MEN-2A syndrome and pulmonary metastasis

  1. J J Alfaro,
  2. C Lamas,
  3. J Estrada,
  4. T Lucas
  1. Division of Endocrinology and Nutrition, Clínica Puerta de Hierro, Madrid, Spain
  1. Correspondence to:
 Dr José Joaquín Alfaro Martínez, Servicio de Endocrinología y Nutrición, Clínica Puerta de Hierro, C/ San Martín de Porres n°4, 28035 Madrid, Spain;
 jalfaro{at}arrakis.es
  • Received 14 March 2001
  • Accepted 24 July 2001

Abstract

A case of multiple endocrine neoplasia syndrome type-2A (MEN-2A) with primary hyperparathyroidism and medullary carcinoma of thyroid initially treated by surgery is reported. The presence of pulmonary nodules six years after the initial treatment was thought to be related to metastasis of medullary carcinoma, and the increase in serum calcium concentrations was assumed to be caused by persistence of parathyroid adenomatous or hyperplastic tissue. The patient underwent surgery again and the pulmonary nodules were confirmed to be metastases of a parathyroid carcinoma, a very rare entity in MEN-2A syndrome.

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