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Postgrad Med J 2001;77:708-712 doi:10.1136/pmj.77.913.708
  • Original article

Adenocarcinoma of the lung in Chinese patients: a revisit and some perspectives from the literature

  1. B Lama,
  2. W K Lama,
  3. C L Lama,
  4. G C Ooib,
  5. J C M Hoa,
  6. M P Wongc,
  7. K W Tsanga
  1. aUniversity of Hong Kong, Queen Mary Hospital, Hong Kong SAR: University Department of Medicine, bUniversity Department of Diagnostic Radiology, cUniversity Department of Pathology
  1. Dr Kenneth W Tsang, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, Chinakwttsang{at}hku.hk
  • Received 23 January 2001
  • Accepted 17 May 2001

Abstract

AIM To establish an updated clinical profile of adenocarcinoma of the lung.

DESIGN Retrospective review of clinical charts, chest radiography, and computed tomography of consecutive patients who attended Queen Mary Hospital in Hong Kong between June 1995 and December 1997.

RESULTS In the 115 patients studied, 13% were <40 years of age (33.3% ever smokers). Haemoptysis is more common among patients with early disease, while finger clubbing was detected more commonly among smokers and ex-smokers. Most (98.3%) patients had abnormal chest radiology including presence of mass lesion, pleural effusion, collapse/consolidation, and effusion. Patients with adenocarcinoma were significantly more likely to be younger, female, in advanced disease (stage IIIB and IV), non-smoker, and symptomatic on presentation (p<0.05) than those with squamous cell lung cancer (n=128).

CONCLUSION The clinical profile of Chinese adenocarcinoma patients should help clinicians in the diagnosis and management of these patients.

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