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Postgrad Med J 2000;76:303-304 doi:10.1136/pmj.76.895.303
  • Case report

Phaeochromocytoma unearthed by fluoxetine

  1. A S Kashyap
  1. Department of Medicine, Armed Forces Medical College, Pune, India
  1. Dr A S Kashyap, 3-B Wanowrie Road, Pune 411040, India
  • Received 23 April 1999
  • Accepted 8 October 1999

Abstract

Non-specific noradrenaline reuptake inhibition by high dose selective serotonin reuptake inhibitors, along with catecholamine release from phaeochromocytoma, may lead to a hypertensive paroxysm. This may unmask a clinically silent phaeochromocytoma. Hypertensive paroxysm induced by paroxetine leading to detection of phaeochromocytoma has been reported. The first patient in whom fluoxetine unmasked a phaeochromocytoma is reported.

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