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Postgrad Med J 2000;76:103-104 doi:10.1136/pmj.76.892.103
  • Short report

An aggressive intrasinusoidal lymphoma presenting with marked systemic disturbance but normal imaging studies

  1. Ross Camidgea,
  2. Edmund Onga,
  3. Helen Lucraftb
  1. aNewcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK Infectious Diseases Unit, bNorthern Centre for Cancer Treatment
  1. Dr Lucraft
  • Received 9 March 1999
  • Accepted 7 June 1999

Abstract

A patient with an aggressive intrasinusoidal non-Hodgkins lymphoma, presenting with marked systemic disturbance but only a mildly raised alkaline phosphatase as a localising sign is described. All imaging studies of the liver were normal and the diagnosis was delayed until a percutaneous liver biopsy was performed. Once diagnosed, the patient responded extremely well to conventional anti-lymphoma chemotherapy.

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