Fatal phenytoin hypersensitivity syndrome
- aNorthwick Park and St Mark's Hospitals NHS Trust, Watford Road, Harrow HA1 3UJ, UK Department of Cellular Pathology, bDepartment of General Medicine and Endocrinology
- Dr E Leen, Histopathology Laboratory, James Connolly Memorial Hospital, Blanchardstown, Dublin 15, Ireland
- Accepted 7 June 1999
Abstract
The phenytoin (hydantoin) hypersensitivity syndrome is rare but potentially fatal. Often, as in this case, it presents with non-specific symptoms and signs, requiring a high degree of clinical suspicion for diagnosis.









