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Postgrad Med J 1999;75:734-737 doi:10.1136/pgmj.75.890.734
  • Short report

Fatal phenytoin hypersensitivity syndrome

  1. U Mahadevaa,
  2. M Al-Mrayatb,
  3. K Steerb,
  4. E Leena
  1. aNorthwick Park and St Mark's Hospitals NHS Trust, Watford Road, Harrow HA1 3UJ, UK Department of Cellular Pathology, bDepartment of General Medicine and Endocrinology
  1. Dr E Leen, Histopathology Laboratory, James Connolly Memorial Hospital, Blanchardstown, Dublin 15, Ireland
  • Accepted 7 June 1999

Abstract

The phenytoin (hydantoin) hypersensitivity syndrome is rare but potentially fatal. Often, as in this case, it presents with non-specific symptoms and signs, requiring a high degree of clinical suspicion for diagnosis.

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