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Postgrad Med J 1999;75:291-293 doi:10.1136/pgmj.75.883.291
  • Short report

Diabetic ketoacidosis precipitated by thyrotoxicosis

  1. A Bhattacharyya,
  2. P G Wiles
  1. Diabetes Centre, North Manchester General Hospital, Crumpsall, Manchester M8 5RB, UK
  1. Dr Wiles
  • Accepted 16 November 1998

Abstract

We report two patients with type 1 diabetes mellitus, previously well controlled with good compliance, presenting with unexplained diabetic ketoacidosis. Following initial correction of the metabolic disorder, persisting tachycardia lead to the diagnosis of thyrotoxicosis. In both cases, treatment with propranolol and carbimazole helped in the stabilization of their metabolic states. Although thyrotoxicosis is known to destabilise diabetes control, we can find no reports of it precipitating diabetic ketoacidosis.

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