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Primary Sjögren's syndrome, ulcerative colitis and selective IgA deficiency.
  1. A. Steuer,
  2. D. J. McCrea,
  3. C. B. Colaco
  1. Central Middlesex Hospital, London, UK.

    Abstract

    A 24-year-old man with primary Sjögren's syndrome presented with xerophthalmia, xerostomia, and marked parotid swelling. He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine. Immunosuppression and withdrawal of sulphasalazine resulted in rapid resolution of the parotitis and disappearance of autoantibodies. A possible role for sulphasalazine in the induction of autoimmunity in this case is discussed.

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