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Successful pregnancy following aplastic anaemia.
  1. K. W. Leong,
  2. A. Teh,
  3. J. J. Bosco,
  4. J. Lim
  1. Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

    Abstract

    Pregnancy following idiopathic aplastic anaemia is rare and is difficult to manage because of life-threatening episodes of bleeding and infections. Only a handful of cases has been reported in the literature. The pregnancies were unsuccessful in the majority. The present report describes a patient with moderately severe idiopathic aplastic anaemia who was managed with intensive haematological support leading to delivery of a healthy infant by caesarean section. Despite platelet transfusion refractoriness as a result of transfusions prior to pregnancy, adequate platelet transfusions prevented excessive bleeding. The literature is reviewed and management with platelet transfusions is discussed.

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