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Postgrad Med J 1995;71:265-268 doi:10.1136/pgmj.71.835.265
  • Research Article

Neurosarcoidosis masquerading as glioma of the optic chiasm in a child.

  1. K. L. Ng,
  2. N. McDermott,
  3. C. A. Romanowski,
  4. A. Jackson
  1. Department of Neuroradiology, Manchester Royal Infirmary, UK.

      Abstract

      We present a case of sarcoidosis in a 14-year-old girl who presented with a short history of visual disturbance. Computed tomography and magnetic resonance imaging (MRI) demonstrated enlargement of the optic chiasm and prechiasmic optic nerves. Post-contrast MRI showed marginal enhancement of the affected areas of the optic pathways. A diagnosis of optic nerve glioma and arachnoid gliomatosis was made; surgical confirmation was not sought due to the risk to vision associated with biopsy. A rapid clinical deterioration led to repeat MRI which demonstrated extensive enhancing soft tissue throughout the basal cisterns with extension into the brain. Biopsy confirmed a diagnosis of sarcoidosis.

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