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Splenectomy in patients with undiagnosed splenomegaly.
  1. C. C. Cronin,
  2. M. P. Brady,
  3. C. Murphy,
  4. E. Kenny,
  5. M. J. Whelton,
  6. C. Hardiman
  1. Department of Medicine, Regional Hospital, Cork, Ireland.

    Abstract

    Of splenectomies performed in the Cork Regional Hospital over an 11 year period, ten were undertaken primarily for diagnostic purposes. A definitive histological diagnosis was established in nine patients, seven of whom had lymphoma, two with Hodgkin's disease and five with non-Hodgkin's lymphoma. The weight of the excised spleen in all patients with lymphoma exceeded 1 kg; in all those with a diagnosis other than lymphoma, the spleen weighed less than 1 kg. A majority of patients also had symptomatic improvement from reversal of hypersplenism and from relief of the mechanical pressure effects of an enlarged spleen. Operative mortality was zero. Diagnostic splenectomy is a worthwhile procedure. Most patients will have lymphoma.

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