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A pharmacokinetic interaction between cimetidine or ranitidine and lornoxicam.
  1. M. Ravic,
  2. I. Salas-Herrera,
  3. A. Johnston,
  4. P. Turner,
  5. K. Foley,
  6. D. E. Rosenow
  1. Department of Clinical Pharmacology, St Bartholomew's Hospital, London, UK.


    Cimetidine 400 mg twice daily significantly increased serum concentrations and reduced apparent oral clearance of lornoxicam 8 mg twice daily in 12 healthy volunteers. Ranitidine 150 mg twice daily produced no significant changes in lornoxicam pharmacokinetics.

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