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Sclerosing cholangitis associated with Crohn's disease and autoimmune haemolytic anaemia.
  1. O. Eilam,
  2. E. Goldin,
  3. D. Shouval,
  4. T. Gimon,
  5. C. Brautbar
  1. Department of Gastroenterology, Hadassah University Hospital, Jerusalem, Israel.

    Abstract

    A middle-aged man was found to have autoimmune haemolytic anaemia. Seven years after the first manifestations of the anaemia, he developed jaundice without haemolysis and a diagnosis of primary sclerosing cholangitis was made by endoscopic retrograde cholangiography. Crohn's colitis was later confirmed by X-rays and colonoscopy. This association is unique to the best of our knowledge and suggests that genetic and immunological mechanisms may be involved in the pathogenesis of these diseases.

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