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Intraocular pressure and pupillary responses in patients with diabetes mellitus.
  1. M. R. al-Sereiti,
  2. P. Turner,
  3. E. A. Gale
  1. Department of Clinical Pharmacology, St Bartholomew's Hospital, London, UK.

    Abstract

    Intraocular pressure (IOP) and the mydriatic responses to darkness in 38 diabetic patients have been compared with those of a matched control group of normal subjects. Overall, the diabetic patients had a significantly higher mean IOP than the control group, but this difference was not found in a sub-group of 13 diabetic patients with evidence of autonomic neuropathy. Those diabetic patients with evidence of autonomic neuropathy had a smaller mydriatic response to darkness than the control group, and this test may usefully be added to standard tests of autonomic function in the diagnosis of autonomic neuropathy.

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