Article Text


Intraocular pressure and pupillary responses in patients with diabetes mellitus.
  1. M. R. al-Sereiti,
  2. P. Turner,
  3. E. A. Gale
  1. Department of Clinical Pharmacology, St Bartholomew's Hospital, London, UK.


    Intraocular pressure (IOP) and the mydriatic responses to darkness in 38 diabetic patients have been compared with those of a matched control group of normal subjects. Overall, the diabetic patients had a significantly higher mean IOP than the control group, but this difference was not found in a sub-group of 13 diabetic patients with evidence of autonomic neuropathy. Those diabetic patients with evidence of autonomic neuropathy had a smaller mydriatic response to darkness than the control group, and this test may usefully be added to standard tests of autonomic function in the diagnosis of autonomic neuropathy.

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