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Type I protein S deficiency and skin necrosis.
  1. A. Craig,
  2. D. A. Taberner,
  3. A. H. Fisher,
  4. D. N. Foster,
  5. J. Mitra
  1. Department of Haematology, Withington Hospital, Manchester, UK.

    Abstract

    A kindred with Type I protein S deficiency is described in which the index case developed skin necrosis during induction of oral anticoagulant therapy for deep venous thrombosis. Two other family members with protein S deficiency have been detected, and demonstrate the clinical variability of this condition.

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