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Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.
  1. M. J. Webberley,
  2. J. A. Murray
  1. Selly Oak Hospital, Birmingham, UK.


    We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide. We describe a possible drug interaction between these two drugs and recommend that they should only be used together with caution.

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