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Postgrad Med J 1987;63:757-759 doi:10.1136/pgmj.63.743.757
  • Research Article

Cyclosporin A in steroid-sensitive nephrotic syndrome with frequent relapses.

  1. M. K. Chan,
  2. I. K. Cheng
  1. Department of Medicine, University of Hong Kong, Queen Mary Hospital.

      Abstract

      Eight patients with steroid-sensitive nephrotic syndrome which frequently relapsed despite cyclophosphamide treatment were given cyclosporin A (7.5 mg/kg/day to 10 mg/kg/day) for 8 to 12 weeks. Six had minimal change glomerulonephritis and two had focal segmental glomerulonephritis. Cyclosporin A was given to 5 patients when their nephrotic syndrome was in relapse and to 3 patients when the nephrotic syndrome was in remission. Cyclosporin A induced a transient remission in only one patient.

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