Postgrad Med J 59:31-33 doi:10.1136/pgmj.59.687.31
  • Research Article

Blood dyscrasias and mianserin.


Four cases are described in which the drug mianserin was implicated in the development of leucopenia. In one case this was accompanied by fatal aplastic anaemia. In a second, generalized bone marrow depression occurred, although leucopenia was the only clinically significant manifestation. Mianserin may depress bone marrow function and haematological surveillance is appropriate for patients taking this drug.