Two cases of biopsy-proven ulcerative colitis are described, and both developed a leucoerythroblastic anaemia during the course of the acute illness. Despite intensive investigation for the presence of bone marrow infiltration, no neoplasm was demonstrated. The leucoerythroblastic anaemia remitted in each case on medical treatment of the ulcerative colitis. The possible mechanisms underlying the development of reversible leucoerythroblastic anaemia are discussed.
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