Postgrad Med J 58:422-423 doi:10.1136/pgmj.58.681.422
  • Papers

Controlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis


A double-blind clinical trial in 60 patients with perennial rhinitis was conducted to compare the efficacy and side effects of two antihistamines, terfenadine and chlorpheniramine maleate, and placebo. There was no statistically significant difference in response between active treatments and placebo. Although side effects were more frequent with chlorpheniramine this also was not statistically significant.