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Postgrad Med J 1981;57:431-432 doi:10.1136/pgmj.57.669.431
  • Research Article

Hypercalcaemia in alphacalcidol therapy.

  1. C. R. Paterson

      Abstract

      Three women with hypoparathyroidism are described who developed severe symptomatic hypercalcaemia while being treated with alphacalcidol (1 alpha-hydroxycholecalciferol; One-Alpha). One sustained permanent renal damage. Alphacalcidol may have advantages over calciferol in its speed of action but poisoning may be more likely to occur. Frequent follow-up checks on the plasma calcium is needed for any patient on alphacalcidol. For long-term management calciferol may still be the drug of choice.

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