A 3-month-old infant with neuroblastoma complicated by progressive depletion of coagulation factors and a microangiopathic haemolytic anaemia is described. Specific anti-tumour therapy corrected the haemorrhagic defect on 2 occasions, but did not affect tumour bulk significantly, although a fall in urinary vanillyl-mandelic acid was seen. The rarity of this association and the possible underlying mechanisms are discussed.
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