The effect of levamisole on different immunological parameters was studied in patients with various malignant diseases.
Levamisole restored tuberculin-negative delayed hypersensitivity reactions and increased the sensitivity to 1-nitro-2,4-dichlorobenzene challenges. It also increased low E-rosette formation of T-lymphocytes and enhanced the clearance of a lipid emulsion by the reticulo-endothelial system.
Levamisole had no effect on serum immunoglobulin levels but increased serum haemolytic complement activity.
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