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Total exchangeable potassium in response to amiloride.
  1. V. R. Pearce,
  2. A. C. Antcliff,
  3. D. G. Beevers,
  4. M. Hamilton

    Abstract

    The use of amiloride is described in twenty-four hypertensive patients who became hypokalaemic as a result of thiazide diuretic therapy in spite of oral potassium supplments. Amiloride caused a significant rise in exchangeable potassium, exchangeable potassium/kg body weight, and plasma potassium, together with a significant fall in plasma total carbon dioxide, body weight, systolic and diastolic blood pressures. These results suggest that amiloride has a useful role in this type of patient.

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