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Gout induced by L-dopa and decarboxylase inhibitors
  1. D. B. Calne,
  2. J. Fermaglich

    Abstract

    Two cases of clinical gout are reported in parkinsonian patients receiving L-dopa in combination with a decarboxylase inhibitor. Blockade of decarboxylation leads to major changes in the pattern of L-dopa metabolites. It is suggested that hyperuricaemia may result from accumulation of L-dopa itself or a transaminated product.

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