A case is described of scleroderma with asymptomatic autoimmune liver disease. The patient presented with the features of CRST syndrome (calcinosis, Raynaud's phenomenon, sclerodactyly and telangiectasia) and a raised plasma alkaline phosphatase was found on routine investigation. It is suggested that this latter biochemical finding is likely to indicate associated autoimmune liver disease in patients with scleroderma.
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