Article Text


Reversible myopathy induced by clofibrate
  1. D. Geltner,
  2. M. Shapiro,
  3. M. Chaco


    A 49-year-old man was given clofibrate in the treatment of hypercholesterolaemia. A myopathy developed accompanied by laboratory enzyme changes and a pathological electromyographic pattern. After ceasing the medication the clinical picture of myopathy disappeared and the enzyme and EMG changes reverted to normal. The EMG changes were once again produced by a short challenge with clofibrate.

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