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  1. H. S Grainger


    At the present time, pharmacopoeias concentrate on defining the active principle of a product, limits of impurities and certain in vitro tests such as disintegration and dissolution rate which have been thought, incorrectly in many instances, to predict absorption characteristics.

    In future, tests must be developed which will more adequately predict bio-availability and these, with information comparing the blood levels and clinical effects of different preparations of drugs, must be available to the prescriber in a pharmacopoeia or other officially recognized compendium.

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