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Megaloblastic anaemia due to trimethoprim-sulphamethoxazole therapy in uraemia
  1. G. M. Yuill

    Abstract

    A patient is described in whom malignant hypertension led to oliguric renal failure. A course of trimethoprim and sulphamethoxazole (co-trimoxazole) was prescribed for an intercurrent urinary tract infection and appeared to precipitate a megaloblastic anaemia which responded satisfactorily to folic acid.

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