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Observations on the treatment of rheumatoid disease with penicillamine
  1. John R. Golding,
  2. J. V. Wilson,
  3. Albert T. Day


    Forty-five patients with severe rheumatoid arthritis were given D-penicillamine hydrochloride according to a fixed regimen for up to 2 years. The effects of treatment were observed both clinically and by the use of laboratory parameters.

    The results show that about 75% of patients exhibited objective improvement. Those with rheumatoid arthritis were found to do particularly well. The incidence, type and severity of side-effects are discussed.

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