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The Kveim test in sarcoidosis
  1. J. R. Mikhail,
  2. D. N. Mitchell

    Abstract

    The Kveim test with a validated test-suspension was found to give an overall 71·9% positive result. A very high figure was obtained among patients with hilar or paratracheal gland involvement.

    Despite our enumeration of the difficulties and drawbacks inherent in Kveim testing, we find that this is a valuable test, providing one is aware of the pitfalls. Despite the finding of positive tests in conditions other than sarcoidosis, these are unlikely in practice to present a clinical problem in the differential diagnosis of suspected sarcoidosis. A microscopically positive test, therefore, remains clinically valuable.

    The test is also of very considerable importance in the clinical research into aetiology and pathogenesis of sarcoidosis.

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