In refractory hypotension of doubtful origin, bacterial factors should be suspected and blood cultures taken. Gram-negative organisms accounted for the majority of cases of bacteraemia.
Unlike haemorrhagic shock, the blood volume estimated in patients in shock associated with infection was not found to be reduced.
In some patients, when vital signs became stabilized, a marked expansion in the vascular capacity was demonstrated.
Plasma of patients in bacteraemic shock was markedly vasoconstrictor.
The metabolic acidosis present in cases of septic shock was due to lactic-acidaemia.
Sepsis can be suspected when thrombocytopenia is associated with leucocytosis.
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