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Pathological fracture of the talar neck associated with amyloid deposition
1 Department of Trauma & Orthopaedic Surgery, Wycombe General Hospital, South Bucks NHS Trust, High Wycombe, UK
2 Department of Histopathology and Cellular Pathology, Wycombe General Hospital, South Bucks NHS Trust, High Wycombe, UK
Correspondence to:
Mr T Christofi, 4E Portman Mansions, Chiltern Street, London W1U 6NS, UK; theodoroschristofi@hotmail.com
Accepted 14 August 2007
Keywords: amyloid; pathological; talus; talar; fractures
| The first 150 words of the full text of this article appear below. |
We present the case of a 61-year-old man who attended our accident and emergency department in January 2007 complaining of pain in his right ankle region. He reported feeling a "crack" in his right foot while walking at home, without any history of trauma. He subsequently developed right heel pain and could only bear weight on his toes. He also reported suffering from longstanding pain in his right ankle, albeit of lesser severity, for the last 3 years. A previous magnetic resonance imaging (MRI) scan of his right ankle, performed in 2004, showed amyloid deposits in the talus but no evidence of cortical discontinuity to suggest a fracture.
The patient suffered from Waldenstrom’s macroglobulinaemia and systemic AL amyloidosis. Amyloid deposition in his kidneys resulted in chronic renal failure requiring maintenance dialysis. He was a non-smoker, otherwise well and not taking any regular medications except calcium supplements.
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