IMAGES IN MEDICINE
Ocular complications in acquired partial lipodystrophy
Dimple Patel, Brian Page
Department of Ophthalmology, Royal Victoria Hospital, Belfast, UK
Correspondence to:
Correspondence to:
Dr D Patel
C/O Department of Ophthalmology, Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BA, UK;dimps88@hotmail.com
Accepted 13 April 2006
Keywords: lipodystrophy; Barraquer–Simons syndrome; drusen; maculopathy
| The first 150 words of the full text of this article appear below. |
A 42-year-old woman with a known diagnosis of acquired partial lipodystrophy (PLD) presented to the ophthalmic clinic with blurring and distortion of vision in the left eye. On general inspection, she had classic lipoatrophy in the cephalothoracic distribution. Ophthalmic examination showed right vision 6/5 and left 6/18. She had marked bilateral drusen and retinal pigment epithelial atrophy of the posterior poles (fig 1
). The left macular also showed a disciform reaction accounting for her visual distortion.
[in a new window] Figure 1 Right fundal photograph showing drusen and retinal pigment epithelial atrophy at the posterior pole.
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Two months later she developed further reduction of left vision to hand motions owing to a dense vitreous haemorrhage. Spontaneous clearance of the vitreous haemorrhage over time disclosed extensive subretinal fibrosis at the left macula (fig 2). The final visual acuity remained hand motions.
[in a new window] Figure 2 Left fundal photograph with extensive subretinal fibrosis.
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To date, no clinical or laboratory evidence
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