© 2004 Fellowship of Postgraduate Medicine
SELF ASSESSMENT QUESTION
Fracture in pregnancy
Pathological fracture in a pregnant woman
Department of Surgery, Tata Memorial Hospital, Mumbai, India
Correspondence to:
Correspondence to:
Dr Pankaj Chaturvedi
Assistant Professor, Tata Memorial Hospital, EB Road, Parel, Mumbai 400 012; pankajch37@yahoo.com
Accepted 15 January 2004
Answers on p 743.
| The first 100% of the full text of this article appears below. |
A 27 year old woman presented in the third trimester of pregnancy with a history of gradually progressive pain in the upper end of her humerus. There was no significant medical history or any other associated illness. Magnetic resonance imaging (MRI) revealed a pathological fracture with extensive marrow replacement of the upper humerus and an associated large soft tissue mass in the upper arm (fig 1
). A core needle biopsy documented benign giant cells. The patient was treated with excision and replacement with a prosthesis.
[in a new window] Figure 1 MRI showing a lytic lesion with pathological fracture and soft tissue extension in the upper end of the humerus.
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- What is the differential diagnosis based on the history and the MRI (giant cell tumour, brown tumour, chondrosarcoma, secondaries in the bone)?
- What other relevant blood investigation should be ordered in such patients (calcium, parathyroid hormone, alkaline phosphatase, acid phosphatase)?
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Pathological fracture in a pregnant woman
Postgrad. Med. J. 2004 80: 743.[Extract] [Full Text] [PDF]
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