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Postgraduate Medical Journal 2003;79:245-246; doi:10.1136/pmj.79.930.245-a
Copyright © 2003 The Fellowship of Postgraduate Medicine.
Postgraduate Medical Journal 2003;79:245-246
© 2003 Fellowship of Postgraduate Medicine

SELF ASSESSMENT ANSWER

Dyspnoea and a subcutaneous swelling

The first 150 words of the full text of this article appear below.

Q1: What does the initial radiograph show (see p 243)?

The initial radiograph shows a homogenous opacity the left hemithorax with a concave upper border, slightly higher laterally, and obscuring the diaphragm and underlying lung.

Q2: What does the radiograph after the chest drain demonstrate (see p243)?

There is marked pleural thickening on the lateral borders of the left hemithorax.

Q3: What is its significance?

Pleural thickening can be due to previous pulmonary infection, infarction, lipoma, lymphoma, tumour, or previous asbestos exposure. More extensive unilateral pleural thickening is usually the result of tuberculous pleuritis, mesothelioma, previous thoracotomy, or pleural effusion.

Q4: What is shown on the chest photograph (see p243)?

There is small round to oval lump in the region of chest drain.

Q5: What is the unifying diagnosis?

Malignant mesothelioma.

Discussion

Mesothelioma may affect pleura, peritoneum or pericardium, the last two sites being less commonly affected than pleura. Malignant mesothelioma is usually due to prolonged exposure to asbestos dust, particularly croccidolite. The tumour characteristically affects 20–40 years after exposure to asbestos. The first symptoms are those associated with worsening dyspnoea, pleural effusions, chest pain, and weight loss. The usual appearance is nodular pleural . . . [Full text of this article]


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Dyspnoea and a subcutaneous swelling
H Ansari and R Bell
Postgrad. Med. J. 2003 79: 243. [Extract] [Full Text] [PDF]

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