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Hyperplastic polyposis coli associated with dysplasia
M A Whittakera, N J Carra, N Crippsba Royal Hospital Haslar, Gosport, UK: Department of Pathology, b Department of Surgery
Correspondence to: Dr M A Whittaker, Department of Histopathology, Queen Alexandra Hospital, Southwick Hill Road, Cosham, Portsmouth, Hampshire PO2 3LY, UK
Submitted 10 April 2000;
Accepted 22 June
2000
| The first 150 words of the full text of this article appear below. |
CASE 1
A 56 year old woman with no previous history of
gastrointestinal disease presented with a short history of abdominal
pain, altered bowel habit, weight loss, and anaemia. There was no mucus or blood in the stool. Colonoscopy revealed a constricting carcinoma at
the hepatic flexure of the transverse colon and numerous sessile and
pedunculated polyps both proximal and distal to the tumour. Subtotal
colectomy with ileosigmoid anastomosis was performed. The resection
specimen showed a Dukes' B adenocarcinoma with vascular invasion and
contained 53 polyps, two of which measured 30 mm in diameter and many
measured around 15 mm; two further polyps were sampled from the
residual colon. Histologically these all proved to be hyperplastic
polyps with two polyps showing foci of low grade dysplasia. The patient
is still being followed up and 10 further small polyps (largest 8 mm)
were found at colonoscopy six months postoperatively. She is a member
of a
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